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The Investigation of Potential Diet Related Risks of Bt Corn in a Long-Term Feeding Study with Laboratory Mice
- Abstract
- In the proposed project 2 groups of laboratory mice are fed with a commercial diet, in which the corn part is substituted by Bt corn in the one diet and with the conventionally grown isoline (33%). It is planned to have 20 pairs per group and to breed 5 generations. The following parameters and methods will be applied:
- general:
feed intake:
growth,
feed conversion rate,
health control.
- reproductive parameters:
litter size and weight,
number of surviving young, rearing success.
- Physiological parameters:
histology of intestine epithelia, lymphatic nodules and spleen,
immunohistochemical tests for Bt antigens
absorption of macro molecules, measuring of the - permeability of the gut wall
Gene expression in the gut wall by means of micro array technique
- Project Leader:
-
Zentek Jürgen,
- Duration:
- 01.12.04-28.02.08
- Type of Research
- Basic Research
- Staff
- Zentek J., Project Leader
- Zentek J., Project Leader
- Vetmed Research Units
-
Institute of Animal Nutrition and Functional Plant Compounds,
- Project partners
- Funded by
-
BM für Gesundheit, Radetzkystrasse 2, 1030 Wien, Austria
- Publications
